Lena Dunham; Max Greenfield; Brandy Clark

Season 21 - Episode 1

From "Girls", creator and actress Lena Dunham; from "New Girl", actor Max Greenfield; musical guest Brandy Clark.

Joel McHale; Marv Albert; Washed Out

Season 21 - Episode 2

From "Community", actor Joel McHale; sportscaster Marv Albert; musical guests Washed Out.

Scarlett Johansson; John Grant

Season 21 - Episode 3

From "Captain America: The Winter Solider", actress Scarlett Johansson; musical guest John Grant.

Anderson Cooper; Bobby Moynihan; Will Hoge

Season 21 - Episode 4

TV host Anderson Cooper; from "Saturday Night Live", comedian Bobby Moynihan; musical guest Will Hoge.

Mindy Kaling; Jeff Altman; Red Fang

Season 21 - Episode 5

From "The Mindy Project", creator and actress Mindy Kaling; stand-up comedy by Jeff Altman; musical guests Red Fang.

Bill Cosby; Sleigh Bells

Season 21 - Episode 6

Comedy legend Bill Cosby; musical guests Sleigh Bells.

Michael Strahan; Jennifer Nettles

Season 21 - Episode 7

From "LIVE with Kelly and Michael", co-host Michael Strahan; musical guest Jennifer Nettles.

Kevin Hart; Mo Rocca; The Orwells

Season 21 - Episode 8

Actor and comedian Kevin Hart; from "My Grandmother’s Ravioli" and "CBS Sunday Morning", journalist Mo Rocca; musical guests The Orwells.

Brian Williams; Rosanne Cash

Season 21 - Episode 9

New anchor Brian Williams; musical guest Rosanne Cash.

Don Cheadle; Myq Kaplan; Roadkill Ghost Choir

Season 21 - Episode 10

From "House of Lies", actor/producer Don Cheadle; stand-up comedy by Myq Kaplan; musical guests Roadkill Ghost Choir.

Andy Samberg; Michael B. Jordan; Ellie Goulding

Season 21 - Episode 11

From "Brooklyn Nine-Nine", actor and comedian Andy Samberg; from "That Awkward Moment", actor Michael B. Jordan; musical guest Ellie Gouldin...

Martin Scorsese; Allison Williams; Cults

Season 21 - Episode 12

From "The Wolf of Wall Street", director Martin Scorsese; from "Girls", actress Allison Williams; musical guests Cults.

Rachel Maddow; Spike Jonze; No Age

Season 21 - Episode 13

TV host and journalist Rachel Maddow; from "Her", director and writer Spike Jonze; musical guests No Age.

Kevin Bacon; Pat McGann; Devon Avenue

Season 21 - Episode 14

From "The Following", actor Kevin Bacon; stand-up comedy by Pat McGann; musical guests Devon Avenue.

Louis C.K.; B.J. Ganem; Artic Monkeys

Season 21 - Episode 15

From "Louie", creator and comic Louis C.K.; Marine veteran B.J. Ganem; musical guests Artic Monkeys.

Eric Stonestreet; Nick Goepper; Bastille

Season 21 - Episode 16

From "Modern Family", actor Eric Stonestreet; freeskier Nick Goepper; musical guests Bastille.

Drew Brees; B.J. Novak; Against Me!

Season 21 - Episode 17

New Orleans Saints quarterback, Drew Brees; actor/author/comedian B.J. Novak; a Top Ten List presented by David Stern; musical guests Agains...

Dr. Phil McGraw; Danny Koker; Dum Dum Girls

Season 21 - Episode 18

TV host Dr. Phil McGraw; from "Counting Cars", TV personality Danny Koker; musical guests Dum Dum Girls.

Bill Murray; Eagulls

Season 21 - Episode 19

From "The Monuments Men", actor/comic Bill Murray; musical guests Eagulls.

Will Arnett; Broken Bells

Season 21 - Episode 20

George Clooney; Sting

Season 21 - Episode 21

Matt Damon; Lenny Kravitz

Season 21 - Episode 22

Patrick Stewart; The Flaming Lips

Season 21 - Episode 23

Regis Philbin; Ms. Lauryn Hill

Season 21 - Episode 24

Kevin Spacey, Amber Heard, a Top Ten List presented by the cast of

Season 21 - Episode 25

Sage Kotsenburg, Kate Mara

Season 21 - Episode 26

Cole Swindell?

Kaitlyn Farrington, Lupita Nyong'o, Little Dragon

Season 21 - Episode 27

Keri Russell, Terry Fator

Season 21 - Episode 28

Pauley Perrette, Jeff Caldwell, Lake Street Dive

Season 21 - Episode 29

Kaley Cuoco-Sweeting, Dale Earnhardt, Jr., The Fray

Season 21 - Episode 30

Olympic Gold Medalist Ted Ligety, Kat Dennings, Lo-Fang

Season 21 - Episode 31

Meredith Vieira, Band of Horses

Season 21 - Episode 32

Stupid Human Tricks, Simon Helberg, Young the Giant

Season 21 - Episode 33

Jack (Jungle) Hanna, Jake Johannsen

Season 21 - Episode 34

Zach Braff, Sgt. Brendan Marrocco & Dr. Andrew Lee, Future Islands

Season 21 - Episode 35

Michael Keaton, Phantogram

Season 21 - Episode 36

Tom Selleck, Carrie Brownstein, David Nail

Season 21 - Episode 37

Tom Brokaw, Andrew Hadlock, Bob Mould

Season 21 - Episode 38

Mary-Louise Parker, Lenny Marcus, Joan Jett & the Blackhearts

Season 21 - Episode 39

Sen. John McCain, Little Mix

Season 21 - Episode 40

Jason Bateman, Miles Teller, Gary Allan

Season 21 - Episode 41

Sylvester Stallone, Theo James, Ledisi

Season 21 - Episode 42

Bryan Cranston, Melissa Rauch, Le1f

Season 21 - Episode 43

Bill O'Reilly, Nick Griffin, the Dough Rollers

Season 21 - Episode 44

Jimmy Carter

Season 21 - Episode 45

Emma Watson, Nick Offerman, a musical tribute to Johnny Cash

Season 21 - Episode 46

Peter Dinklage, Hari Kondabolu, Sage the Gemini

Season 21 - Episode 47

Cobie Smulders, Nick Cannon, Manchester Orchestra

Season 21 - Episode 48

Kristin Chenoweth, Amy Schumer, Johnnyswim

Season 21 - Episode 49

Bill Murray, Martha Stewart, Lady Gaga

Season 21 - Episode 50

Johnny Depp, Kevin Drew

Season 21 - Episode 51

Billy Crystal, Tony Hale, Liv Warfield

Season 21 - Episode 52

Rob Lowe, Brooklyn Decker, London Grammar

Season 21 - Episode 53

Lindsay Lohan, Jamie Edwards, Real Estate

Season 21 - Episode 54

Courteney Cox, Jimmie 'J.J.' Walker, Christina Perri

Season 21 - Episode 55

Stephen Colbert, Robin Roberts, Kelis

Season 21 - Episode 56

Sally Field, Timothy Simons, Needtobreathe

Season 21 - Episode 57

Neil Patrick Harris, Sarah Hyland, Ray LaMontagne

Season 21 - Episode 58

Piedmont Bird Callers, Michael J. Fox, Naughty Boy

Season 21 - Episode 59

Joel McHale, Vera Farmiga, Aloe Blacc

Season 21 - Episode 60

Lucy Liu, Ziggy Marley

Season 21 - Episode 61

Kiefer Sutherland, Adam Resnick, Benjamin Booker

Season 21 - Episode 62

Louis C.K., a performance from the Broadway cast of Rocky

Season 21 - Episode 63

Don Rickles, Carmen Lynch, the Ghost of a Saber Tooth Tiger

Season 21 - Episode 64

Shailene Woodley, Peyton Manning

Season 21 - Episode 65

Jon Cryer, Elizabeth Olsen, Foster the People

Season 21 - Episode 66

Mariah Carey, Rick Harrison

Season 21 - Episode 67

James Franco, Idina Menzel, a performance by the Broadway cast of 'If/Then'

Season 21 - Episode 68

Nathan Fillion, Tom Dreesen, Hunter Hayes

Season 21 - Episode 69

Harry Connick Jr., Jesse Eisenberg, the Black Keys

Season 21 - Episode 70

Jim Parsons, Julie Chen, Hozier

Season 21 - Episode 71

Barbara Walters, Elle Fanning, Randy Houser

Season 21 - Episode 72

Adam Sandler, Thomas Haden Church

Season 21 - Episode 73

Lea Michele, Andy Kindler, Chromeo

Season 21 - Episode 74

Jack Hanna, Stephen Malkmus & the Jicks

Season 21 - Episode 75

Kid scientists, Sarah Silverman, We Are Scientists

Season 21 - Episode 76

Sgt. Kyle J. White, Judy Greer, Dierks Bentley

Season 21 - Episode 77

Donald Trump, Indianapolis 500 winner Ryan Hunter-Reay, Elizabeth Cook

Season 21 - Episode 78

Martin Short, John Oliver, Spanish Gold

Season 21 - Episode 79

Anderson Cooper, Victor Espinoza, the Afghan Whigs

Season 21 - Episode 80

Hugh Jackman, Joe List, Elvis Costello

Season 21 - Episode 81

Kelsey Grammer, Willie Nelson

Season 21 - Episode 82

Dave Chappelle, Laura Prepon, a Top Ten List presented by Miss USA, the Orwells

Season 21 - Episode 83

Christopher Walken, Janelle Monae, Tatiana Maslany, Miss USA 2014

Season 21 - Episode 84

Regis Philbin, Paul Morrissey, First Aid Kit

Season 21 - Episode 85

Susan Sarandon, Whitney Cummings, Angel Olsen, David Sanborn

Season 21 - Episode 86

Olivia Wilde, Shep Gordon, Empires

Season 21 - Episode 87

Dana Carvey, Ellie Kemper, Sam Smith

Season 21 - Episode 88

Paul Rudd, Jeff Altman, John Doe

Season 21 - Episode 89

Adam Levine, Gen. Frank J. Grass, Broken Bells

Season 21 - Episode 90

Melissa McCarthy, Rachelle Lefevre, Phish

Season 21 - Episode 91

Mark Wahlberg, Ben Falcone, Hurray for the Riff Raff

Season 21 - Episode 92

Mark Ruffalo, Former Marine Lance Cpl. William 'Kyle' Carpenter

Season 21 - Episode 93

Halle Berry, Steve Young, War on Drugs

Season 21 - Episode 94

Joan Rivers, Capital Cities

Season 21 - Episode 95

Lizzy Caplan, Sleeper Agent

Season 21 - Episode 96

Michael Douglas, Paul Morrissey, Kiesza

Season 21 - Episode 97

Kurt Russell, Hannibal Buress, Sturgill Simpson

Season 21 - Episode 98

Jason Segel, Liv Tyler, Trampled By Turtles

Season 21 - Episode 99

Emma Stone, Nathan Fielder, American Authors

Season 21 - Episode 100

Colin Firth, Tommy Johnagin, EMA

Season 21 - Episode 101

Jeff Daniels, Norah O'Donnell, A Special Performance of 'MacArthur Park'

Season 21 - Episode 102

Dave welcomes actor Jeff Daniels, "CBS This Morning" co-anchor Norah O'Donnell, and a performance of the song "MacArthur Park" by an all-sta...

Ricky Gervais, Taylor Schilling, Eli Young Band

Season 21 - Episode 103

Eric Stonestreet, Brody Dalle

Season 21 - Episode 104

Staff Sgt. Ryan Pitts, Sharon Van Etten

Season 21 - Episode 105

John C. Reilly, Rachelle Lefevre, Conor Oberst

Season 21 - Episode 106

Chris Pratt, Rodrigo y Gabriela

Season 21 - Episode 107

Zoe Saldana, Crash

Season 21 - Episode 108

Julia Louis-Dreyfus, Simon Amstell, David Gray

Season 21 - Episode 109

Bruce Willis, the Gaslight Anthem

Season 21 - Episode 110

Joseph Gordon-Levitt, Novak Djokovic, Robby Johnson

Season 21 - Episode 111

Kathy Griffin, Ken Burns, Jeremy Messersmith

Season 21 - Episode 112

Serena Williams, Chadwick Boseman, Echo & the Bunnymen

Season 21 - Episode 113

Michael Cera, dock diving dogs, Lyle Lovett

Season 21 - Episode 114

Howie Mandel, EMA

Season 21 - Episode 115

James McAvoy, Chris Russo, The Last Internationale

Season 21 - Episode 116

Mike Myers, Bonnie McFarlane, John Fullbright

Season 21 - Episode 117

Luke Wilson, Julie Chen, Lee Brice

Season 21 - Episode 118